The Kanohar Lal Trust Society established Kanohar Lal Mahila Mahavidyalaya in 1969 to provide educational facilities to children and women in and around the city of Meerut. On 22 November 1968, the foundation stone of the college was laid by the Governor of Uttar Pradesh, B. Gopal Reddy and the Late Shri Seth Kanohar Lal ji, to open a women's degree college, came true. The dream to open a women's college had its roots in the foresight and steely determination of Seth Kanohar Lal who understood the dire need of the times; lack of educational resources for women and the paucity of women empowerment in the society. In a brief span of seven months, a huge two-storey building was constructed. The total area of the college is dream of 12439 sq. Metres or 3.073 acres.

On 5th July 1969, the Chief Minister of Uttar Pradesh, Shri Chandra Bhanu Gupta inaugurated the college. Established in the year of Gandhi’s birth centenary , this college is imbued with the thoughts of Mahatma Gandhi and Ba Kasturba, "Simple living, high thoughts" and the great message of Lord Buddha "Appa Deepo Bhava". The admission of 250 girl students in the very first session clearly validated the importance of building this college. In September 1969, the college was included under the UGC Act 1956, 2(4). Since its inception, it has laid emphasis on discipline and academics. Co-curricular facilities like National Cadet Corps, National Service Scheme and Rover-Rangers are also available for the students along with Sports.